Poster: Cellular fluorescein hyperfluorescence is dynamin-dependent and is increased with Tetronic 1107 treatment
Tahmina Khan is a PhD graduate from the Division of Pharmacy and Optometry, University of Manchester, UK, whose research focussed on investigating clinical SICS using an in vitro model. Tahmina is now a chemistry specialist for the Health and Safety Executive, UK. Download the poster (.pdf), which was originally shared at the International Society for Contact Lens Research (ISCLR) meeting, Washington, US, 2017. The feature article of this issue of Contact Lens Update reviews the full paper by Khan et al on their work with cellular fluorescein hyperfluorescence and dynamin, where they demonstrate, via in vitro model, that fluorescein uptake into cells is an active process, which is enhanced in the presence of the surfactant Tetronic 1107 (found in some multipurpose care solutions) This poster preceded the paper, and was presented at ISCLR, Washington, US, 2017. It provides a short, easily digestible summary of the work.