Evidence-Based Efficacy of Myopia Control Interventions
Dr Noel A. Brennan is Research Fellow at Johnson & Johnson Vision, where he has been since 2011. Prior to that he co-directed a privately-owned research consulting company and, before that, was an academic faculty member at the University of Melbourne, reaching the level of Reader. Download the poster (.pdf), which was originally shared at the American Academy of Optometry (AAO) annual meeting, 2018. Evidence-Based Efficacy of Myopia Control Interventions Noel A. Brennan1 MScOptom, PhD, FAAO Xu Cheng1 MD, PhD, FAAO Mark Bullimore2 MCOptom, PhD, FAAO, FARVO 1. Johnson & Johnson Vision 2. Independent Consultant Purpose Decision-making in modern clinical practice is increasingly dependent on evidence-based medicine. Previous analyses of the efficacy of myopia control interventions have delivered results as percentage or absolute reduction in myopia progression over a given time frame. Estimates of longer term efficacy have been constructed around these estimates but fail to account for two important recent observations: (i) myopia control efficacy tends to an absolute effect rather than a relative effect across the progression range, and (ii) efficacy may decrease over time on both absolute and relative bases. Here, we apply the principles of evidence-based medicine to efficacy of myopia control interventions. Methods We systematically reviewed the literature, including relevant peer-reviewed conference abstracts, to categorize quality of investigations of a set of myopia control interventions currently of interest (see Table) based on adherence to evidence-based principles. The only indisputable metric than can be used is data-driven estimates of cumulative absolute reduction in progression rather than absolute annual or relative rates. … [ Read More ]
