Eric Papas has written a fascinating editorial describing how our appreciation of SICS has changed over time, concluding with some present day evidence [ Read More ]
Cellular fluorescein hyperfluorescence is dynamin-dependent and increased by Tetronic 1107 treatment
David McCanna reviews Tahmina Khan’s in vitro work which examines the mechanism of fluorescein uptake into cells, and how this is modulated by a particular surfactant found in some MPS [ Read More ]
A new SICS factsheet is available for practitioners to download, providing a summary of key information about SICS along with advice on how to deal with it in practice. [ Read More ]
Poster: Cellular fluorescein hyperfluorescence is dynamin-dependent and is increased with Tetronic 1107 treatment
Tahmina Khan is a PhD graduate from the Division of Pharmacy and Optometry, University of Manchester, UK, whose research focussed on investigating clinical SICS using an in vitro model. Tahmina is now a chemistry specialist for the Health and Safety Executive, UK. Download the poster (.pdf), which was originally shared at the International Society for Contact Lens Research (ISCLR) meeting, Washington, US, 2017. The feature article of this issue of Contact Lens Update reviews the full paper by Khan et al on their work with cellular fluorescein hyperfluorescence and dynamin, where they demonstrate, via in vitro model, that fluorescein uptake into cells is an active process, which is enhanced in the presence of the surfactant Tetronic 1107 (found in some multipurpose care solutions) This poster preceded the paper, and was presented at ISCLR, Washington, US, 2017. It provides a short, easily digestible summary of the work.