Staining Wars
Eric Papas has written a fascinating editorial describing how our appreciation of SICS has changed over time, concluding with some present day evidence Continue reading
Staining
Cellular fluorescein hyperfluorescence is dynamin-dependent and increased by Tetronic 1107 treatment
David McCanna reviews Tahmina Khan’s in vitro work which examines the mechanism of fluorescein uptake into cells, and how this is modulated by a particular surfactant found in some MPS Continue reading
Practitioner Reference: Evolving our Understanding of SICS
A new SICS factsheet is available for practitioners to download, providing a summary of key information about SICS along with advice on how to deal with it in practice. Continue reading
Poster: Cellular fluorescein hyperfluorescence is dynamin-dependent and is increased with Tetronic 1107 treatment
The feature article of this issue of Contact Lens Update reviews the full paper by Khan et al on their work with cellular fluorescein hyperfluorescence and dynamin, where they demonstrate, via in vitro model, that fluorescein uptake into cells is an active process, which is enhanced in the presence of the surfactant Tetronic 1107 (found in some multipurpose care solutions) This poster preceded the paper, and was presented at ISCLR, Washington, US, 2017. It provides a short, easily digestible summary of the work. Continue reading
