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Issue 09 | June 2012
Drug delivery via contact lenses
Contact lenses able to deliver drugs via the eye will revolutionize patient care. In this issue, Alex Hui provides an overview of past and current research; Chau-Minh Phan reviews a study investigating the use of contact lenses to deliver cyclosporin A as a dry eye treatment (Peng and Chauhan, 2011); Anthony Soluri reports success in delivering ketotifen fumarate to the eye via contact lenses; and Alisa Sivak reports on Noel Brennan’s BCLA talk about the regulatory hurdles facing this new technology.
- Editorial - Contact lenses for drug delivery – overview and recent developments
- Feature Article - Delivering cyclosporine A from contact lenses: An article review
- Conference Highlights - Ocular delivery of ketotifen fumarate by silicone hydrogel and conventional hydrogel contact lens materials
- Clinical Insight - Barriers to drug delivery via contact lenses: A report from the 2012 BCLA meeting
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Issue 08 | May 2012
Ocular allergies
Ocular allergies can have a significant impact on our patients — particularly those who wear contact lenses. In this issue of Contact Lens Update, James Wolffsohn and Paramdeep Singh Bilkhu explore ways of helping patients maintain contact lens wear despite allergies; Bernardo Cavalcanti and Candice Williams demonstrate the use of confocal microscopy to investigate corneal and conjunctival changes in patients with ocular allergies; Fiona Soong reviews an article (Mark Abelson, 2003) on the pathophysiology of ocular allergies; and Ulli Stahl and Jalaiah Varikooty demonstrate slit lamp techniques differentiating folliculosis from phlyctenulosis.
- Editorial - Maintaining contact lens wear in patients with allergic conjunctivitis
- Feature Article - Pathophysiology of allergic eye disease
- Conference Highlights - In vivo confocal microscopy as a tool to evaluate cellular changes in the cornea and conjunctiva in ocular allergy and non-allergic ocular inflammatory diseases
- Clinical Insight - Visualization of limbal/conjunctival folliculitis associated with soft contact lens wear
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Issue 07 | March 2012
Reducing lens case contamination
Epidemiological studies have linked poor lens case hygiene with increased risk of developing serious conditions like microbial keratitis. Even tightly-controlled clinical trials report case contamination as high as 92% overall and 15-45% with potentially pathogenic bacteria. In this edition of Contact Lens Update, Mark Willcox outlines new disinfection guidelines and tools; David McCanna reviews an article (Willcox 2010) detailing just what kinds of microorganisms you might find living on a contact lens case and their persistence when exposed to marketed lens care systems, and Mark Willcox focuses on the efficacy of one multipurpose system in particular. Don't miss the opportunity to tell us what you think of silver-infused lens cases and heat-based disinfecting strategies, in our extended reader poll -- located under Clinical Insights.
- Editorial - Review of recent development to reduce contact lens case contamination
- Feature Article - How safe is your lens case?
- Conference Highlights - Effect of a MPDS containing Polyquaternium-1 and Alexidine dihydrochloride on contamination of contact lens cases
- Clinical Insight - Effective care of contact lens cases: What do you think?
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Issue 06 | January 2012
Dry eye and meibomium gland dysfunction
With dry eye cited as a major reason for contact lens dropout, it's no wonder that we continue to search for answers as to its cause, most effective assessment and potential treatments. In this edition of Contact Lens Update, Kelly Nichols outlines the essential components to cover in a five-minute ocular surface exam; Sruthi Srinivasan looks at the possibility of a connection between contact lens wear and meibomian gland dysfunction; Etty Bitton summarizes key points in a recent review of the past, present and future of meibomian gland dysfunction; and Alisa Sivak reviews research presented at the 2011 annual meeting of the American Academy of Optometry.
- Editorial - Contact lens wear and meibomian gland dysfunction
- Feature Article - The past, present and future of meibomian gland dysfunction: A review
- Conference Highlights - Meibomian gland dysfunction: An update from the 2011 meeting of the American Academy of Optometry
- Clinical Insight - Five-minute ocular surface exam in a contact lens practice