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Relation between subjective responses to contact lens wear and compliance in children

September 20th, 2018
Rebecca Weng headshotRebecca Weng manages clinical trials and facilitates myopia project collaboration in China. She is also the program facilitator for BHVI's myopia program.

Download the poster (.pdf), which was originally shared at the Association for Research in Vision and Ophthalmology (ARVO) annual meeting, 2018.


Relation Between Subjective Responses to Contact Lens Wear and Compliance in Children
Rebecca Weng, Ravi C Bakaraju, Xiang Chen, Wayne Li, Thomas Naduvilath, Padmaja Sankaridurg

Purpose: To evaluate the relation between subjective responses to contact lenses (CL) wear and compliance in children when they were assigned wearing either single vision (SVCL) or novel CL designed to control progression of myopia.

Methods: A retrospective, case control analysis of a clinical trial conducted in Guangzhou, China where children (n=523) aged 7 to 13, spherical equivalent between -0.75D and -3.50D were randomized into one of 5 groups: a control group with SVCL, 2 groups wearing extended depth of focus CL (EDOF 1 or 2) and 2 groups wearing myopia defocus CL (MDCL 1 or 2). A self-administered questionnaire gathered subjective responses related to ocular comfort and vision at various distances, ghosting, night haloes and vision stability at 1, 3 and 3 monthly intervals thereafter for 2 years on a numerical scale (1-10 where 1 is poor and 10 is excellent). Compliance to lens wear was categorized as lens wear for ≤ 5 days/week (non-compliant) and ≥ 6 days/week (compliant). Data were collated and differences between groups analyzed using linear mixed models adjusted by visits with the interaction between lens type and visits assessed (p<0.05).

Results: On average, 79% of the SVCL subject visits and 68% of the novel CL subject visits were compliant. In general, subjective ratings were rated significantly higher for compliant subjects in all responses except for haloes (p<0.05). Lens types also played a significant role in rating vision stability while walking, play sport, and while walking up and down stairs between compliant and non-compliant subjects (p<0.05). Differences between compliant and non-compliant subjects were greatest for comfort (approximately 1 or greater grade) followed by vision stability while walking and playing sport. Differences were least for clarity of vision at near (less than 1 grade) and more variability in subjective rating was seen between visits among the non-compliant subjects. Subjective ratings showed an improvement from baseline in grades over time for the compliant subjects.

Conclusions: Differences exist between compliant and non-compliant children for CL related comfort and vision including those wearing SVCL. A higher subjective rating may indicate that the children are more satisfied with their lens wearing experience, therefore are likely to wear CL more frequently, adhering to the wearing schedule set out in the study.

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