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Struggle with soft contact lens wear is addressed by refitting with daily disposable lenses

November 29th, 2013
photo_bio_robinRobin Chalmers is a clinical trials consultant based in the United States.

Download the poster (.pdf), which was originally shared at the Annual Meeting of The Association for Research in Vision and Opthalmology (ARVO), 2013.


Struggle with soft contact lens wear is addressed by refitting with daily disposable lenses

Robin L. Chalmers1, Sheila Hickson-Curran2, Lisa Keay3, Bill Gleason4, Roger Albright4

1 Clinical trials consultant, USA
2 Johnson & Johnson Vision Care Inc., USA
3 The George Institute, Australia
4 Foresight Regulatory Strategies, Inc., USA

Purpose: To describe which gaps in soft contact lens (SCL) performance were addressed by refitting habitual SCL wearers with silicone hydrogel (SiHyDD) or hydrogel daily disposable (HydDD) lenses in the 1-DAY ACUVUE® TruEye® or 1-DAY ACUVUE® MOIST® Performance Overview (TEMPO) Registry (#NCT01467557).

Methods: Self-administered questionnaires (n=598) from participants who completed Baseline, 2 Week and 4 Month questionnaires were analyzed for differences at baseline and change over time by habitual lens group (Reusable SiHy n=369, Reusable Hyd n=59, Hydrogel DD n=170). Change in Contact Lens Dry Eye Questionnaire–8 (CLDEQ-8) score, hours of comfortable wear, self-rating of ease of use and compliance with instructions for wear were tested with t-tests or Wilcoxon Signed Rank tests by habitual lens group and new lens brand.

Results: The CLDEQ-8 score improved significantly for all treatment arms (Baseline mean ranged from 11.6±6.2 for HydDD habitual SCLs to 15.9±7.1 for Reusable Hyd) at all visits except for the Hyd to HydDD group at the 4 month visit (p<0.0004, all other comparisons). Symptoms of dryness and discomfort improved more among SiHyDD wearers compared to HydDD, but improvement in intensity of blurry vision was equivalent for the two DD lenses. Mean wearing times were unchanged but mean comfortable wearing time improved by 1.0 to 2.3 hours (p

Conclusions: Responses from this observational, practice based study show the patient’s perspective on SCL wear after changing to these SiHyDD and HyDD lenses. The primary advantages noted were in reduction in dryness and discomfort symptoms, lengthening of comfortable wearing time and expected improvements in ease of use and compliance with instructions offered by the DD modality.

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