• About Us
  • Privacy
  • Contact Us

Contact Lens Update

Clinical Insights Based in Current Research

Search Our Site

  • Home
  • Browse Past Issues
  • Resource Library
  • Back to Basics
  • Useful Links
  • About Us
  • Contact Us

Conference Highlights

Associations between solution induced corneal staining, corneal infiltrative events, and Gram-­negative bacteria case contamination

November 6th, 2012
Daniel Tillia is a research optometrist at the Brien Holden Vision Institute, a part-time clinical supervisor at the School of Optometry and Vision Science, University of New South Wales, Australia, and occasionally works in private practice.

Download the poster (.pdf), which was originally shared at the British Contact Lens Association’s Clinical Conference and Exhibition, 2012


Associations between solution induced corneal staining, corneal infiltrative events, and Gram­ negative bacteria case contamination

1Daniel Tilia, M.Optom, 1Hua Zhu, Ph.D, 1Varghese Thomas, B.Sc, 2Mark Wilcox, Ph.D, 2,3Brien Holden, Ph.D, 1,2Percy Lazon de la Jara, Ph.D

1Brien Holden Vision Institute, University of New South Wales, Sydney, Australia;2School of Optometry and Vision Science, University of New South Wales, Sydney, Australia; 3Vision Cooperative Research Centre, Sydney, Australia.

Corresponding Author: d.tília@brienholdenvision.org

Purpose: To compare incidences of solution ­induced corneal staining (SICS), corneal infiltrative events (CIEs) and Gram-negative bacteria case contamination (GNBCC) rates between five lens care products (LCPS) when used with the same silicone hydrogel contact lens.

Method: Rates for SICS, CIE and GNBCC for LCPs (AOSEPT Plus [AOSP]: H202, CIBA; Synergi: sodium chloríte/H202, Sauflon; Complete RevítaLens MPDS [CRL]: polyqyaternium-1/alexidine dihydroschloride, AMO; Biotrue: polyquaternium­1/PHMB, B+L;,  AQuífy: PHMB, CIBA) when used with balafilcon A (B+L)  lenses were obtained either from published data or calculated retrospectively. All studies followed a similar protocol. SICS and CIE incidences were reported as occurrence per 100 participant-months. Analysed cases were used for one month and number colony forming units of GNB counted after culture. Antìbacterìal cases were used with Synergì, polypropylene with CRL, Bìotrue and AQuify. Rates were compared using Fìsher’s exact test with Bonferroni adjustment for multiple comparisons. Statistical significance was set at p<0.05.

Results: Percentage rates for SICS/CIE/GNBCC for each LCP were AOSP: 0.9/0/-, Synergi: 0.9/0/1/4, CRL: 5.1/0/11.8, Biotrue: 29.0/1.8/15.9, AQuify: 21.9/4.0/28.8.  The oxidative LCPs (AOSP/Synergi) were significantly lower than PHMB containing LCPs for SICS (0.9%v25.6%, p<0.001), CIEs (0%v2.8%, p=0.01) and GNBCC (1.4%v21.9%, p<0.001).  Oxidative LCPs were significantly lower and the alexidine containing LCP for SICS (5.1%, p=0.04) and GNBCC (Synergi only)(11.8%, p=0.02) but not CIEs (0%, p>0.05).  The alexidine LCP was significantly lower than PHMB LCPs for SICS (p<0.001) but not CIEs (p>0.05) or GNBCC (p>0.05).

Conclusions: When used with balafilcon A, oxidative LCPs have lower rates of SICS. Efficacy against GNBCC might reduce CIE incidence.

 

Related Articles

  • November 6, 2012

    Is the solution the real solution?

  • November 6, 2012

    How effective are contact lens care solutions?

  • November 6, 2012

    Associations between solution induced corneal staining, corneal infiltrative events, and Gram-­negative bacteria case contamination

  • November 5, 2012

    Solution-induced corneal staining: Review and case study

Issues

  • Multifocal Contact Lenses
  • Artificial Tears: An Update
  • Myopia: New Evidence and Best Practices
  • Neuropathic Pain
  • Specialty Rigid Lenses
  • Contact lens compliance
  • Pandemic update
  • Digital Devices and Dry Eye: A Growing Issue
  • The long and short of axial length
  • Using BCLA CLEAR with your patients
  • Helping your patients through allergy season
  • Getting the measure of meibomian glands
  • 2020: An extraordinary year
  • Scleral lens update
  • A dose of myopia
  • New news since TFOS DEWS II
  • COVID-19 Special Edition
  • Material considerations
  • Putting dry eye theory into practice
  • Getting started with Ortho-K
  • Infiltrates – an update
  • Staining
  • Myopia matters: Summarising the IMI reports
  • Lids and contact lenses
  • Myths
  • Revisiting patient compliance
  • Contact Lenses & Kids
  • Interprofessional Collaboration
  • Digital eye strain
  • New Dry Eye Technology
  • Update on Presbyopia
  • Taking stock of dry eye disease: DEWS II
  • Scleral Lenses
  • Pain and Sensation
  • Lab measurements in clinical practice
  • Control of pediatric myopia
  • Nutrition
  • Rethinking contact lens deposits
  • Extended wear
  • Daily Disposables
  • Eyelash Mites (Demodex)
  • Outsmarting bacteria with new technology
  • Youth and contact lenses
  • Sports Vision
  • Ocular effects of UV radiation from the sun
  • Eyelid Conditions
  • Makeup: Impact on ocular health
  • Myopia Control – Update 2014
  • The Growing Prevalence of Myopia
  • Cosmetic contact lenses
  • Contact lens discomfort – The essentials
  • Technology and contact lens research
  • It's A Question of Comfort
  • Contact lens materials
  • Let's talk about SICS
  • Conjunctival Controversies
  • Kids & Contact Lenses
  • One-day silicone hydrogel lenses
  • Solutions
  • Spotlight on Scleral lenses
  • Drug delivery via contact lenses
  • Ocular allergies
  • Reducing lens case contamination
  • Dry eye and meibomium gland dysfunction
  • Myopia Control
  • Presbyopia
  • Compliance and non-compliance
  • Lens care
  • Celebrating 50 years of contact lenses

Looking for another article?

Alcon coopervision Johnson&Johnson Vision Care

Newsletter Sign-Up

Sign-up for and start receiving our newsletter.

Site Map

  • Home
  • Browse Past Issues
    • Editorial
    • Feature Article
    • Clinical Insight
    • Conference Highlights
  • Resource Library
  • Back to Basics
  • Useful Links
  • About Us
  • Contact Us
© 2023 Contact Lens Update